Starch 1500® Almidón de maíz parcialmente pre-gelatinizado

Assessment of Low Dose Content Uniformity of Indomethacin

Comparison of excipients and content uniformity in a formula containing a very low dose of indomethacin

Direct Compression Formulation of Loratadine (10 mg) Tablets

Starch 1500 in a lactose free, low dose active formulation, loratadine

Formulación de un Suplemento Dietético de Melatonina de Liberación Prolongada

Debido a la corta vida media de la melatonina, las empresas nutra se enfrentan al desafío de diseñar comprimidos de liberación prolongada. Aprenda cómo la hipromelosa puede ser una solución.

Formulating Veterinary Tablets for Palatability and Acceptance es

Formulation of Veterinary Chewable Tablets

Formulation of Veterinary Chewable Tablets - Case Study with Carprofen

Increasing the Compactability of Echinacea Purpurea Powder using Starch 1500®

Treating a high dose, poorly compressible herbal powder with Starch 1500 and fumed silica to increase compressibility

Lactose Replacement with Starch 1500® in a direct compression formula

Robust, more stable placebo tablet via DC compared to a similar lactose based formulation

Replacement of Di Basic Calcium Phosphate with Starch 1500® in a DC Formula

Benefits of using Starch 1500 in a DC placebo formulation replacing DCP

Starch 1500® as a Binder and Disintegrant in XCH (Xiaochaihu) Herbal Extract/Powder Tablet

High dose tablet formulation of XCH herbal extract/powder combination using Starch 1500/MCC in a high-shear granulation process

Starch 1500® used as a Binder Disintegrant in High Shear Wet Granulation Comparison to Povidone and Croscarmellose Sodium

Starch 1500 reduces overall cost and complexity of a formulation, in comparison to povidone and croscarmellose sodium

Wet Granulation of Acetaminophen with Starch 1500®

Improvement in tablet hardness and disintegration of Starch 1500 vs PVP

Free and Bound Water in Starch 1500® compared to other excipients

Comparison of Water Activity vs LOD of commonly used excipients.

Technical Bulletin: Starch 1500®

Typical properties and key applications for Starch 1500 in oral solid dose formulation

AAPS 2005 - Particle Swelling and Coalescence to Gel Layer Formation

Swelling and coalescence behavior of HPMC and Starch 1500, in order to monitor the contribution to gel layer formation in matrices.

AAPS 2006 - Modulation of Drug Release from Hypromellose (HPMC) Matrices: Suppression of the Initial Burst Effect

Method to minimize a burst of drug release typically observed in the early phases of release of highly soluble actives from METHOCEL matrices.

AAPS 2010 - Effect of Filler Type on Low Dose Acetaminophen Hydrophilic Matrix Formulations

Effect of four commonly used fillers in formulation and processing of HPMC matrices utilizing a high shear wet granulation process.

AAPS 2010 - Influence of Filler Type in the Blend Uniformity of Micronized Drugs

Choice of filler for a low-dose micronized drug to assist dispersibility and uniformity of the drug

AAPS 2011 - Barrier Membrane Coating of Hydrophilic Matrices of Sparingly Soluble Drug, Acetaminophen: A Strategy to Reduce Possible Food Effect

Application of a barrier membrane (BM) coating consisting of Surelease and a pore-former, Opadry.

AAPS 2011 - Effect of Drug Particle Size on Blend Segregation and Content Uniformity of Low Dose Tablets

Low dose formulations of micronized hydrochlorothiazide (HCTZ) & the effect of drug particle size and load on dissolution rate

AAPS 2012 - Barrier Membrane Coated Hydrophilic Matrices: Robustness of Metoprolol Tartrate Release under Biorelevant Test Conditions – Impact of Media Composition

Joint poster - Ernst Moritz Arndt University & Colorcon

AAPS 2012 - Investigation of Synergistic Behavior of Excipients in Direct Compression Using a Rotary Press Simulator

Use of Starch 1500 in combination with MCC in direct compression.

AAPS 2012 - Stability of Ethylcellulose Barrier Membrane Coated Hydrochlorothiazide Matrices Comprising Starch 1500® or Lactose as Filler

Starch 1500 contributed to robustness of the barrier membrane coated matrix tablets.

AAPS 2015 - Eliminating Burst Release of Highly Soluble Drug from Hydrophilic Matrix Tablets Using Venlafaxine as a Model Drug

Combination of ionic low viscosity polymer with high viscosity Hypromellose reduced drug release within first 2 hours of dissolution.

AAPS 2015 - Enhancing the Stability of a Famotidine Tablet Formulation through Use of Starch 1500®

The low water activity of Starch 1500 resulted in reduced degradation of famotidine. Starch/MCC formulation, coated with a PVA based Opadry® resulted in an improved accelerated stability in blister packages.

AAPS 2021 - Dissolution of Glucosamine Veterinary Chewable Tablets Using Ultra High Performance Liquid Chromatography-Charged Aerosol Detection es

CRS 2010 - Effect of Processing Conditions on Hypromellose Matrix Formulations of Acetaminophen Prepared by a High Shear Wet Granulation Process

Processing guidelines for developing a hypromellose matrix formulation using a wet granulation process; with extra-granular addition of HPMC and Starch 1500 resulting in increased tablet hardness.

CRS 2011 - Use of Starch 1500® to Minimize Variability on Drug Release from Hypromellose Matrices

Starch 1500 in formulation design, supporting QbD study and minimizing formulation variability

Effect of Filler Type on the Stability of Polyethylene Oxide in a Hydrophilic Matrix Tablet

The effect of various fillers on the oxidative stability of POLYOX in a matrix tablet

Formulating TCMs; East meets West

How formulated coated tablets can make Traditional Chinese Medicine more palletable

Formulating Veterinary Chewable Tablets to Improve Palatability and Acceptance

Formulation of Acetylsalicylic Acid Tablets for Aqueous Enteric Film Coating

Combination of excipients for an aspirin tablet core suitable for aqueous enteric film coating

Formulation of Low Dose Medicines - Theory and Practice

Evaluating multiple excipients for content uniformity in a low dose application

Influence of Excipients on Drug Release from Hydroxypropyl Methylcellulose Matrices

JOURNAL OF PHARMACEUTICAL SCIENCES, VOL. 93, NO. 11, Nov 2004

Multifunctional Excipients

Pharma Magazine Sept/Oct 2006

Starch Contrasts

Review of differences among pregelatinized starches - morphology, particle size and how the degree of modification effects functionality.

The Effect of Core Design and Formulation on the Quality of Film Coated Tablets

Article published in Pharmaceutical Technology Europe - April 2005