Back
Picking and Sticking
Tablet Core
- Poor adhesion to core Use high adhesion core excipients
Coating Formulation
- Poor film adhesion Select a high adhesion film coating from Colorcon
- Low solids film coating formulation Select a high solids film coating from Colorcon
Process/Equipment
- Spray rate too high Decrease spray rate
- Drying air volume too low Increase airflow rate
- Drying air temperature too low Increase drying temperature
- Pan speed too low Increase pan speed
- Atomization air pressure too low Increase atomization air pressure
- Pan load too low Increase pan load
- Poor spray uniformity Increase number of spray guns, fan width and/or gun-to-bed distance, suspension flow rate balance