AAPS 2010 - Effects of Core Tablet Size on the Functionality of Aqueous Delayed Release Coatings as Measured by SEM and LIBS

The aim of this work was to develop a correlation between tablet surface area (size) and the minimum amount of coating weight gain/thickness of a functional coating necessary for enteric protection of tablets. The film coat thickness was determined via scanning electron microscopy (SEM) and laser-induced breakdown spectroscopy (LIBS).Acryl-EZE 93O formulations